BBC Sport’s chief football writer Simon Stone:
Pep Guardiola has never made any secret of his belief Rodri is irreplaceable as a single midfield anchor in his Manchester City side.
Kalvin Phillips is the nearest thing to a sitting midfielder in the City squad but Guardiola has long since decided the former Leeds man is not good enough and he is currently on loan at Ipswich and unable to be recalled until January.
That means Guardiola is likely to tinker with his formation and play with two holding midfielders.
Former Chelsea star Mateo Kovacic can fill that role but he is not the only option.
Centre-back John Stones has rarely played as a lone defensive midfielder during his time at Etihad, but has been inverted into the deep-lying role at times from central defence and right-back.
Ilkay Gundogan was used in that position on numerous occasions before he left for Barcelona in 2023. Bernardo Silva has also played there, as has currently sidelined Kevin de Bruyne at times.
And then there is 19-year-old Rico Lewis, who someone Guardiola said only last week could fill a number of positions, such is his flexibility.
Losing Rodri for any length of time would be a hammer blow for City, but if anyone can come up with a plan to deal with it, Guardiola can.
The January transfer window is only a few months away as well.
Former Premier League striker Chris Sutton told Radio 5 live’s Monday Night Club: “I don’t think anybody can fill that role like Rodri, but Kovacic is as able a replacement out there. We’ve seen in the past they will find a way of coping, they always do.”