Wasps beat reigning champions Harlequins for the first time in the Premier 15s as they claimed a 30-14 bonus-point win.
Heather Cowell’s try put Harlequins in front, but Wasps responded with scores from Maud Muir, Ellie Boatman and Bryony Cleall.
Abby Dow went over early in the second half to seal an emphatic victory, although Rosie Galligan scored for Quins late on at the Coventry Building Society Arena.
Second-placed Bristol Bears missed the chance to keep the pressure on leaders Saracens as they drew 26-26 against Loughborough Lightning.
Hannah West, Jasmine Joyce, Rownita Marston and Kayleigh Powell touched down to give the Bears a 26-12 half-time lead at Shaftesbury Park.
But the visitors produced a stunning comeback through tries from Lark Davies and Charli Jacoby, who powered over with seven minutes to go.
Saracens, who host second-bottom Sale Sharks on Sunday, are three points ahead of Bristol.
Exeter Chiefs moved above Quins and into third as they ran in 14 tries in a 90-7 thrashing of DMP Durham Sharks.
Jennine Detiveaux scored a first-half hat-trick and four tries in total at Sandy Park.
In the day’s late kick-off, Emma Sing converted a late penalty and give seventh-placed Gloucester-Hartpury a 15-12 win over Worcester, who remain one spot behind them in the table.
Gloucester-Hartpury were 12-0 up at the break after tries at the start and very end of the first half from Bethan Lewis and Sisilia Tuipulotu.
However, Worcester came back into it as Cat McNaney crossed in the corner 10 minutes into the second period.
Taz Bricknell then muscled over with 13 minutes left and Sarah Nicholas converted to level the scores at 12-12.
That led to a frantic finale before Gloucester-Hartpury were awarded a penalty with four minutes to go and Sing held her nerve.